1. State Key Laboratory of Powder Metallurgy, Central South University, Changsha 410083, China; 2. Xiangya Hospital, Central South University, Changsha 410083, China; 3. College of Biology, Hunan University, Changsha 410083, China
Abstract In order to meet the clinical requirements for corrosion resistance and osteogenesis of magnesium-based metal implants, the dense and uniform Mg-Fe-layered double hydroxide (Fe-LDH) coatings were prepared on the AZ91D Mg alloy matrix by hydrothermal method and the Fe-LDH/AZ91D samples were obtained. Electrochemical and hydrogen evolution experiments were performed to explore the effects of coatings on corrosion resistance and its in-vitro performance. Combining CCK-8 and in-vitro mineralization experiments, the biocompatibility and osteogenic properties of Fe-LDH/AZ91D were studied. The results show that the existence of the Fe-LDH coating establishes a barrier between AZ91D and the corrosive liquid and improves the corrosion resistance of the alloy. The corrosion inhibition efficiency of the modified magnesium alloy reaches 92.76%. After immersion in PBS for 14 days, the mass loss rate of AZ91D (40.59%) is almost 1.6 times that of Fe-LDH/AZ91D (25.16%), and the corrosion rate (4.14 mm/a) is about twice that of Fe-LDH/AZ91D (2.13 mm/a). The leaching solutions with different Fe-LDH/AZ91D volume fractions have good cell compatibility and can maintain the osteogenic activity of the cells, reaching the same level as the control group.
JING Shaohui,ZHOU Jixiang,ZHAO Dapeng, et al. Corrosion resistance, in-vitro degradation and osteogenic properties of AZ91D alloy modified by Mg-Fe-LDH coating[J]. Materials Science and Engineering of Powder Metallurgy, 2022, 27(5): 509-518.
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2022, Vol. 27 
