水热法制备光热治疗剂纳米WO3-x的组织结构与光热效应

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Abstract PTMP-PMAA modified Nano-WO_3-_x powder was obtained by hydrothermal method. The effects of pH value and concentration on photothermal properties of the nano-WO_3-_x powder materials were studied by X-ray diffraction (XRD), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), UV-vis spectroscopy and photothermal property testing. The results show that the powders prepared by hydrothermal method are spherical nonintegral structure W₁₇O₄₈ with a particle size of less than 10 nm. The UV absorbance of the WO_3-_x material increases and the photothermal effect increases with decreasing the pH value or concentration of WO_3-_x. When pH 6.4 and mass concentration is 800 μg/mL, the temperature of WO_3-_x can rise nearly 19 ℃ in 5 minutes after photothermal conversion. Considering that the body temperature is 37 ℃ and the pH value of tumor site is between 6.0 and 6.5, nano-WO_3-_x powders at this concentration can be used in photothermal therapy and achieve the killing effect on tumor cells.

Key words： hydrothermal method WO_3-_x pH value concentration photothermal effect ultraviolet absorption

Received: 14 May 2018 Published: 12 July 2019

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Cite this article:

HU Wei,HUANG Zhi. Microstructure and photothermal effect of photothermal agent nanocrystalline WO_3-_x prepared by hydrothermal method[J]. Materials Science and Engineering of Powder Metallurgy, 2019, 24(1): 37-44.

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http://pmbjb.csu.edu.cn/EN/ OR http://pmbjb.csu.edu.cn/EN/Y2019/V24/I1/37

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